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Updated: Jun 23, 2025

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动物模型和arrhythmogenic心肌病变的分子发病因子与间隔盘基因中的致病变异相关

Sara Vencato1, Chiara Romanato1, Alessandra Rampazzo1

  • 1Department of Biology, University of Padova, Via U. Bassi 58/B, 35121 Padova, Italy.

International journal of molecular sciences
|June 19, 2024
PubMed
概括

节律失调性心肌病 (ACM) 是一种遗传性心脏病,由纤维脂肪组织替代引起. 鼠类模型显示Wnt/β-catenin和Hippo通路参与了ACM病变发生.

关键词:
节律失常性心肌病变性心脏病变症间隔式光盘 间隔式光盘 间隔式光盘鼠标模型 鼠标模型病原性机制的病原性机制

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Mechanism of Cardiac Arrhythmias01:28

Mechanism of Cardiac Arrhythmias

Arrhythmias are irregular heart rhythms occurring when the heart's electrical impulses become abnormal. These disturbances can lead to various symptoms, depending on their severity and the underlying cause. Some common factors contributing to arrhythmias include hypoxia, ischemia, electrolyte imbalances, excessive catecholamine exposure, drug toxicity, and muscle overstretching. Arrhythmias can be classified into two main types based on the rate and site of origin of abnormal heart rhythms.
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