饮食蔬菜和水果消费与萨科佩尼亚的关联:系统性审查和元分析
Seung-Hee Hong1, Yun-Jung Bae2
1Department of Food and Nutritional Science, Shinhan University, Uijeongbu 11644, Gyeonggi, Republic of Korea.
Nutrients
|June 19, 2024
概括
吃蔬菜和水果与较低的肉症风险有关,这种疾病会导致肌肉损失. 这一元分析证实了农产品消费对肌肉健康的保护作用,特别是在老年人中.
科学领域:
- 老年学是指老年学的学科.
- 营养流行病学 营养流行病学
- 公共卫生 公共卫生
背景情况:
- 标志着与年龄相关的肌肉质量和力量损失的萨尔科佩尼亚,构成了重大的公共卫生挑战.
- 以前关于蔬菜和水果摄入量与肉症风险之间的关联的研究已经产生了不一致的结果.
- 饮食模式,特别是水果和蔬菜的消费,越来越多地被认为对减轻与年龄相关的健康衰退的潜在作用.
研究的目的:
- 进行全面的元分析,评估蔬菜和水果消费与患上沙科佩尼亚的风险之间的关联.
- 综合现有观察性研究的证据,以更好地理解这种关系.
- 坚持系统审查和元分析 (PRISMA) 首选报告项目指南的方法严格性.
主要方法:
- 在PubMed,EMBASE和Cochrane图书馆进行了系统的文献搜索,直到2023年7月.
- 包括的研究是观察性的,包括横截面和队列设计.
- 用一个随机效应模型计算95%信心区间 (CI) 的聚合几率比率 (ORs),以考虑异质性.
主要成果:
- 分析包括14项观察性研究,共33801名参与者和6436例肉症病例.
- 总体而言,蔬菜和水果消费与降低了肉症风险的显著关联 (OR,0.61;95% CI,0.48至0.79).
- 这种保护性关联在横截面研究和60岁及以上的参与者中显著,但在队列研究中不一致.
结论:
- 这些发现表明,更多的蔬菜和水果消费与较低的肉类的风险有关.
- 虽然证据是有希望的,特别是对于老年人,进一步的高质量前性队列研究是有必要的,以证实这些发现,因为他们提供更高水平的证据.
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