在分娩时与胎盘相关的参数与不同怀孕期间的叶酸补充有关
Yating Ren1,2,3, Maoyuan Yang1, Siyi Ren1
1School of Public Health, Anhui Medical University, Hefei 230032, China.
Nutrients
|June 19, 2024
概括
在怀孕前和怀孕期间补充叶酸会对胎盘发育产生积极影响. 早期使用叶酸会增加胎盘的宽度和面积,而在怀孕后期使用会增加胎盘厚度.
科学领域:
- 产科和妇科 产科和妇科
- 营养科学 营养科学
- 发展生物学 发展生物学
背景情况:
- 叶酸 (FA) 对于DNA合成,修复和甲基化至关重要.
- 大多数研究集中在FA对胎儿发育的影响上,对胎盘发育的研究有限.
- 在怀孕期间对FA补充剂和胎盘发育缺乏基于人口的研究.
研究的目的:
- 调查在不同怀孕阶段补充叶酸对分娩时胎盘参数的影响.
- 分析叶酸使用 (怀孕前,早期,中期和晚期) 与胎盘尺寸之间的关联.
主要方法:
- 一项针对中国2708名孕妇的基于人口的研究.
- 从怀孕前一个月到分娩,收集关于叶酸使用的数据.
- 测量胎盘的长度,宽度和厚度.
- 使用多变量逻辑回归和倾向得分加权的统计分析.
主要成果:
- 怀孕前补充叶酸与胎盘宽度 (0.241厘米) 和表面积 (6.398厘米2) 的增加有关.
- 怀孕早期使用叶酸与胎盘厚度增加 (0.061厘米) 相相关.
- 在怀孕中期使用叶酸也与胎盘厚度增加 (0.066厘米) 相相关.
结论:
- 怀孕前补充叶酸会对胎盘宽度和表面积产生积极影响.
- 在怀孕早期和中期服用叶酸与胎盘厚度增加有关.
- 建议进行进一步的研究,以验证这些关于叶酸在胎盘发育中的作用的发现.
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