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身体活动和饮食对癌症患者的联合影响:系统性审查和元分析
Petros C Dinas1,2, On Behalf Of The Students Of Module Introduction To Systematic Reviews1, Marianthi Karaventza1
1Department of Nutrition and Dietetics, School of Physical Education, Sport Science and Dietetics, University of Thessaly, 42130 Trikala, Greece.
结合体力活动和营养干预措施,有望改善癌症患者的治疗结果. 这些生活方式的改变可以减少体重,炎症和抑郁,同时提高生活质量.
科学领域:
- 在瘤学瘤学.
- 运动科学 运动科学
- 营养科学 营养科学
背景情况:
- 癌症患者和癌症幸存者通常会在生物标志物,生活质量和心理健康方面经历有害的变化.
- 越来越多地探索生活方式干预措施来减轻这些不良影响.
研究的目的:
- 系统地审查和元分析联合体育活动/运动和饮食/营养干预措施的影响.
- 评估各种癌症类型对生物/生化指数,生活质量 (QoL) 和抑郁症的影响.
主要方法:
- 按照PRISMA指南和"柯克兰手册"进行的系统审查和元分析.
- 在PROSPERO注册的协议 (注册号:CRD42023481429).
主要成果:
- 中等质量的证据表明,联合干预可以降低体重,脂肪量,胰岛素,HOMA-IR,C反应蛋白,甘油三和抑郁症.
- 在高密度脂蛋白,物理QoL成分和癌症治疗的一般功能评估中观察到的改善.
结论:
- 综合体力活动和营养干预措施可以减少体重,脂肪量,胰岛素和炎症.
- 这些干预措施可以改善癌症患者和癌症幸存者的脂质概况,身体质量和抑郁症.
- 结果表明癌症发生风险的潜在降低,尽管适用性因人口和干预异质性而异.
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