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右侧大动脉门:计算机断层扫描血管学调查,系统性审查与元分析
George Triantafyllou1, Savvas Melissanidis2, Marianna Vlychou3
1Department of Anatomy, School of Medicine, Faculty of Health Sciences, National and Kapodistrian University of Athens, 115 27 Athens, Greece.
Journal of clinical medicine
|June 19, 2024
概括
右侧大动脉 (RAA) 是一种罕见的大动脉变异. 这项研究发现了它在希腊人口中的患病率,并分析了变体,并指出与先天性心脏缺陷的关联.
科学领域:
- 心血管解剖学 心血管解剖学
- 放射学 放射学是一门学科.
- 医学遗传学 医学遗传学
背景情况:
- 右侧大动脉 (RAA) 是一种不常见的大动脉 (AA) 变异,大动脉穿过右侧主支气管.
- RAA呈现出下降大动脉位置 (脊柱的右侧或左侧) 的变化.
- 由于可能与先天性心脏异常和干预风险同时发生,RAA具有临床意义.
研究的目的:
- 用计算机断层扫描血管学 (CTA) 来确定希腊人口中RAA的患病率.
- 进行RAA形态变异的系统审查和元分析.
- 为改善临床实践提供RAA特征的见解.
主要方法:
- 对于200个CTA进行RAA识别的回顾性分析.
- 在PubMed,Google Scholar和Scopus的系统文献搜索AA形态学研究.
- 使用R编程语言和RStudio进行聚合流行率元分析,包括子组分析.
主要成果:
- 一个独特的RAA病例 (200个CTA中的0.5%) 呈现出一个特定的分支序列:RSA,RCCA,LCCA和LVA起源于来自Komerell分离器的ALSA.
- 对62项研究 (72,187例) 的元分析估计,RAA与镜像形态的综合流行率为0.07%.
- 随着异常左下关节动脉 (ALSA) 的RAA的患病率估计为<0.01%.
结论:
- 像RAA这样的AA异常需要临床关注,因为它们与先天性心脏缺陷有关 (例如,Fallot四重律,PFO).
- 了解RAA患病率和变体对于在干预期间管理潜在并发症至关重要.
- 这项研究强调了识别RAA及其相关心脏异常的重要性.
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