机会性切除术对卵巢储备的影响:系统性审查
Teodora Radu1,2, Matyas Mar1,2, Vlad Tudorache1,2
1Department of Obstetrics and Gynecology, "George Emil Palade" University of Medicine, Pharmacy, Sciences and Technology, 540142 Târgu-Mures, Romania.
Journal of clinical medicine
|June 19, 2024
概括
双边切除术 (BS) 可以通过切除输卵管来帮助预防卵巢癌. 目前的证据表明,BS对卵巢储备没有短期的负面影响,但长期的影响需要进一步研究.
科学领域:
- 妇科 妇科 妇科 妇科
- 在瘤学瘤学.
- 生殖医学 生殖医学
背景情况:
- 新出现的证据表明,高度的血清性卵巢癌起源于输卵管.
- 预防性双侧切除术 (BS) 是为平均风险妇女提出的卵巢癌预防策略.
- BS对卵巢储备的影响需要在各种手术背景下进行调查.
研究的目的:
- 审查双边切除术对卵巢储备的潜在负面影响.
- 为了评估子宫切除术,剖腹产和辅助生殖技术后的BS影响.
- 为了评估BS可能会损害卵巢功能的假设.
主要方法:
- 在PubMed,Medline,Google Scholar和Cochrane数据库中进行全面的文献搜索.
- 包括2014年至2024年间发表的原始研究,元分析和意见文章.
- 在对114个记录进行初步选后,对102个相关文章进行了系统审查.
主要成果:
- 机会性切除术似乎对卵巢功能没有直接的不良影响.
- 人们担心在手术过程中卵巢血液供应可能受到损害.
- 短期数据显示,对卵巢储备没有显著的负面影响.
结论:
- 双边沙切除术对卵巢癌的预防有前途,对卵巢储备没有明显的短期损害.
- 由于血液供应受损,可能对卵巢储备产生长期不良影响,需要进一步调查.
- 关于卵巢储备的BS安全性需要继续研究,特别是长期结果.
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