由于抗癌疗法导致的皮肤恶性瘤
Michela Starace1,2, Luca Rapparini1,2, Stephano Cedirian1,2
1Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.
Cancers
|June 19, 2024
概括
化疗和向疗法等癌症治疗方法会增加皮肤癌的风险. 早期检测和查对于接受抗癌治疗的患者来说至关重要,以有效地管理这些风险.
科学领域:
- 在瘤学瘤学.
- 皮肤病学 皮肤病学
- 癌症治疗方法 癌症治疗方法
背景情况:
- 皮肤癌是癌症治疗中的一个重要问题.
- 各种抗癌治疗与患皮肤癌的风险增加有关.
研究的目的:
- 综合审查不同抗癌疗法与皮肤癌风险之间的关联.
- 要突出与各种治疗剂相关的特定皮肤癌类型.
主要方法:
- 在接受抗癌疗法的患者中检查皮肤癌风险的研究文献综述.
- 对将特定治疗方法与基底细胞癌 (BCC),皮肤状细胞癌 (cSCC),皮肤黑色素瘤 (CM) 和非黑色素瘤皮肤癌 (NMSC) 联系起来的数据分析.
主要成果:
- 甲托雷克萨特 (MTX),弗鲁达拉宾,基尿素 (HU),易布鲁替尼,雅努斯激酶抑制剂 (JAKi),基因激活蛋白激酶通路 (MAPKP) 抑制剂,声波刺通路 (SHHP) 抑制剂和放射治疗与皮肤癌风险增加有关.
- 具体的关联包括MTX与BCC,cSCC和CM;化疗剂与NMSC;针对性治疗与NMSC和CM;MAPKP抑制剂与cSCC和第二原发性黑色素瘤 (SPMs);SHHP抑制剂与cSCC;和放射治疗与BCC.
结论:
- 了解与抗癌治疗相关的各种皮肤癌风险至关重要.
- 对接受这些治疗的患者实施适当的查方案对于有效的管理和改善结果至关重要.
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