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Updated: Jun 23, 2025

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
10:33

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Published on: October 26, 2015

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作为多向的Clk/Dyrk抑制剂和潜在的抗癌剂的N-基化5-基二二胺

Noha Mostafa1,2, Po-Jen Chen3,4, Sarah S Darwish1,5

  • 1Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo 11835, Egypt.

Cancers
|June 19, 2024
PubMed
概括

针对Dyrk1A,Dyrk1B和Clk1的新型激酶抑制剂显示出作为抗癌疗法的前景. 化合物12和17有效抑制癌细胞生长,并诱导细胞亡,对健康细胞的影响最小.

关键词:
5 - 基基基基基基基一个小小的东西.迪尔克1AA 在线观看诱导性亡诱导性亡细胞周期分析分析细胞周期分析多个目标的多重定位.

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