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Updated: Jun 23, 2025

Chemoselective Preparation of 1-Iodoalkynes, 1,2-Diiodoalkenes, and 1,1,2-Triiodoalkenes Based on the Oxidative Iodination of Terminal Alkynes
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Chemoselective Preparation of 1-Iodoalkynes, 1,2-Diiodoalkenes, and 1,1,2-Triiodoalkenes Based on the Oxidative Iodination of Terminal Alkynes

Published on: September 12, 2018

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终端基因对于MAO-A/MAO-B抑制是必要的吗? 一个新的脚手架被揭示出来

Panagiou Mavroeidi1, Leandros P Zorba1, Nikolaos V Tzouras1

  • 1Laboratory of Organic Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, 15771 Athens, Greece.

Molecules (Basel, Switzerland)
|June 19, 2024
PubMed
概括

研究人员使用多元组分反应开发了新型的propargylamines. 这些化合物对人类单胺氧化酶 (hMAO) -A和hMAO-B酶表现出显著的抑制活性,为神经退行性疾病治疗提供了潜力.

关键词:
在MM/GBSA中使用.分子动力学分子动力学一种单氨基氧化剂.甲基胺的使用方法

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