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Updated: Jun 23, 2025

Capture Compound Mass Spectrometry - A Powerful Tool to Identify Novel c-di-GMP Effector Proteins
12:11

Capture Compound Mass Spectrometry - A Powerful Tool to Identify Novel c-di-GMP Effector Proteins

Published on: March 29, 2015

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通过分子动力学模拟,解开循环腺-氨基单酸盐 (cAIMP) 对STING的结合模式

Meiting Wang1,2, Baoyi Fan1, Wenfeng Lu1

  • 1School of Medical Engineering & Henan International Joint Laboratory of Neural Information Analysis and Drug Intelligent Design, Xinxiang Medical University, Xinxiang 453003, China.

Molecules (Basel, Switzerland)
|June 19, 2024
PubMed
概括

循环氨酸-氨酸单酸相似物 (cAIMPs) 将人类的STING (hSTING) 结合到U形形状,稳定了蛋白质. 分子动力学揭示了关键的相互作用和对免疫反应中STING激活至关重要的结构变化.

关键词:
刺痛是一种刺痛.绑定模式 绑定模式cAIMP 这是一个很好的方法.形状的变化 形状的变化免费能源计算的免费能源计算分子动力学分子动力学

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A Pipeline to Investigate the Structures and Signaling Pathways of Sphingosine 1-Phosphate Receptors12:27

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