在天然聚合物涂层中封装活性物质
Emma Akpo1, Camille Colin1, Aurélie Perrin1
1IEM, Université de Montpellier, CNRS, ENSCM, F-34095 Montpellier, France.
Materials (Basel, Switzerland)
|June 19, 2024
概括
封装使用生物聚合物保护活性成分,提供可控释放. 本综述详细介绍了用于智能药物输送系统的封装技术和天然聚合物.
科学领域:
- 材料科学 材料科学 材料科学
- 化学工程是化学工程的重要组成部分.
- 生物技术是生物技术.
背景情况:
- 封装保护活性成分免受降解,并控制它们在各种行业中的释放.
- 生物聚合物是理想的墙壁材料,因为它们具有生物相容性,生物降解性和无毒性,形成"智能"水凝屏障.
- 控制释放对于优化治疗疗效和产品稳定性至关重要.
研究的目的:
- 提供封装技术和机制的全面概述.
- 探索天然聚合物作为封装墙壁材料.
- 为不同的药物确定具有成本效益和合适的封装方法.
主要方法:
- 对封装技术的审查,包括微型和纳米凝.
- 对受控释放机制 (扩散和屏障降解) 的分析.
- 对作为墙壁材料使用的天然聚合物的调查.
主要成果:
- 生物聚合物形成水凝,作为受控释放的响应性屏障.
- 各种天然聚合物显示出作为封装材料的前景.
- 不同的聚合物为特定的药物输送应用提供了明显的优势.
结论:
- 使用生物聚合物进行封装提供了一种多功能方法,用于控制活性成分的输送.
- 天然聚合物为药物封装提供了一个可持续和有效的替代品.
- 进一步的研究可以为特定的制药,化品和农业化学应用优化聚合物选择.
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