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相关概念视频

Precipitation of Ions03:11

Precipitation of Ions

Predicting Precipitation
The equation that describes the equilibrium between solid calcium carbonate and its solvated ions is:
Colloidal precipitates01:09

Colloidal precipitates

The high insolubility of some precipitates can result in an unfavorable relative supersaturation. This can lead to colloidal particles with a large surface-to-mass ratio, where adsorption is promoted. For instance, in the precipitation of silver chloride, silver ions are adsorbed on the surface of the colloidal particles, forming a primary layer. This layer attracts ions of opposite charge (such as nitrate ions), forming a diffuse secondary layer of adsorbed ions. This electric double layer...
Ion Exchange01:17

Ion Exchange

Ion exchange chromatography separates charged molecules from a solution by reversibly exchanging them with mobile, or 'active', ions associated with the oppositely charged stationary phase. This method can be used to separate ions, soften and deionize water, and purify solutions. The polymers comprising the ion-exchange column are high-molecular-weight and chemically stable polymers, crosslinked to be porous and essentially insoluble. They are also functionalized with either acidic or basic...
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Capillary zone electrophoresis (CZE) separates ionic components based on their electrophoretic mobility. It has been used to separate proteins, amino acids,...
The Electrical Double Layer01:30

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In the region where two bulk phases meet, an intricate electric charge distribution arises due to charge transfer, ion adsorption, molecular orientation, and charge distortion. This complex distribution is commonly referred to as the electrical double layer.When a solid electrode interfaces with ions in an electrolyte solution, the speed of electron transfer dictates the rates of oxidation and reduction. The electrode acquires a charge through the escape of atoms into the solution as cations or...

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Generation and Recovery of β-cell Spheroids From Step-growth PEG-peptide Hydrogels
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电化学扩散研究在聚乙烯糖醇 (PEG) 基二甲基酸盐基凝中.

Eva Melnik1, Steffen Kurzhals1, Giorgio C Mutinati1

  • 1Molecular Diagnostics, AIT Austrian Institute of Technology GmbH, 1210 Vienna, Austria.

Sensors (Basel, Switzerland)
|June 19, 2024
PubMed
概括

聚乙烯甘) 二甲基酸盐 (PEG-DMA) 水凝的特征是用于传感器应用. 研究人员发现,水凝网格大小对小分子和蛋白质扩散性产生影响,显示了生物感应试剂储存的潜力.

关键词:
结合MB蛋白质的结合蛋白质.扩散性研究的研究.电化学传感器 电化学传感器这种水凝是水凝.甲基烯蓝色是什么意思

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科学领域:

  • 材料科学 材料科学 材料科学
  • 生物技术是生物技术.
  • 分析化学 分析化学

背景情况:

  • 水凝对于传感器和微流体的功能化至关重要.
  • 聚乙烯甘二甲酸盐 (PEG-DMA) 是可打印水凝前体油墨的常见粘性剂.

研究的目的:

  • 用于传感器应用的PEG-DMA水凝的特征.
  • 为了研究这些水凝中的小分子和蛋白质的扩散性.
  • 探索水凝作为生物感知试剂储存器的潜力.

主要方法:

  • 使用重力测量和电化学方法对1-10kDa的PEG-DMA水凝进行表征.
  • 计算膨胀比率 (SRs) 和网格大小 (ξ).
  • 用修改的传感器对甲基蓝 (MB) 和MB结合蛋白进行电化学测量.

主要成果:

  • 胀率 (SR) 与PEG-DMA分子度 (MCI) 相对应.
  • 网格大小 (ξ) 与PEG-DMA分子量 (Mw) 相对应.
  • 水凝修饰减少了MB,MB-BSA和MB-IgG的峰值电流,随着网格大小的增加,扩散性增加.
  • 在水凝干燥后成功检测到MB-BSA释放.

结论:

  • 根据度和分子量,可以调整PEG-DMA水凝的特性.
  • 水凝网格大小影响小分子和蛋白质扩散,影响传感器性能.
  • 干燥的PEG-DMA水凝显示出作为生物感应应用的稳定试剂储的前景.