勃起功能障碍的年轻男性自发性勃起功能恢复,每天服用一次5毫克的塔达拉菲尔
Edoardo Pozzi1,2,3, Christian Corsini1,2, Alessandro Bertini1,2
1Department of Urology, University Vita-Salute San Raffaele, Via Olgettina, 58, 20132 Milan, Italy.
The journal of sexual medicine
|June 19, 2024
概括
每天服用塔达拉菲尔 (每天一次) 有效地治疗年轻男性的精神性勃起功能障碍 (ED). 大多数患者在停止服用药物后实现自发勃起功能恢复,年轻年龄与更高的恢复率相关.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 安德罗学与人类学
- 药理学 药理学是指药理学的学科.
背景情况:
- 每天服用塔达拉菲尔 (每天服用一次) 是治疗勃起功能障碍 (ED) 的一种选择,特别是对于喜欢自发的男性.
- 这项研究研究了在停止每天一次服用5毫克塔达拉菲尔后,在患有心理性勃起障碍的年轻男性中,自发性,无药性勃起功能 (EF) 的恢复.
研究的目的:
- 为了评估自发性,无药性勃起功能 (EF) 恢复的速度,在停止每天服用5毫克一次的塔达拉菲尔后.
- 确定与EF恢复相关的临床因素,以年轻男性的初级心理性ED.
主要方法:
- 分析了96名50岁以下的男性患者,新诊断出精神性ED,每天服用一次达拉菲尔5毫克治疗.
- 使用国际勃起功能指数 (IIEF) 评估自发性勃起功能恢复后的塔达拉菲尔停药.
- 包括考克斯回归和卡普兰-梅尔曲线在内的统计分析,以确定影响EF恢复的因素.
主要成果:
- 85.4%的患者在停止每天一次服用5毫克塔达拉菲尔后实现了自发EF恢复.
- 年龄较小与EF恢复的可能性更高显著相关 (HR 0.95,P=0.01).
- 停药后3个月的康复率为43%,6个月的康复率为60%,停药后12个月的康复率为72%.
结论:
- 塔达拉菲尔5毫克每天服用一次,对于心理性ED的短期治疗是有效的,从而使其能够在随后的无药EF恢复.
- 年轻的年龄是预测成功自发勃起功能恢复治疗停止后达拉菲尔治疗的一个关键因素.
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