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Herniated Intervertebral Disc l: Introduction01:29

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Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...

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用于预测术后复发性腰椎椎间盘的诺莫грам开发和验证,基于类脊椎肌肉参数.

Ming Tang1,2, Siyuan Wang1,2, Yiwen Wang1

  • 1Department of Interventional Vascular Medicine, Hefei Hospital Affiliated to Anhui Medical University, The Second People's Hospital of Hefei, Hefei City, Anhui Province, People's Republic of China.

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副脊髓肌肉骨肌肉指数 (SMI) 预测了手术后的椎间盘的复发情况. 一个Nomogram模型准确地评估了经皮内镜转椎间盘切除术 (PETD) 后患者患上术后复发性腰椎间盘 (PRLDH) 的风险.

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腰椎椎间盘的发生通过皮肤进行的内透镜转膜椎间隔切除术.术后复发的腰椎间盘椎间盘.预测模型是一个预测模型.

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科学领域:

  • 脊柱外科手术 脊柱外科手术
  • 整形外科 整形外科 整形外科
  • 放射学 放射学是一门学科.

背景情况:

  • 副脊柱肌肉对于脊柱的稳定性至关重要.
  • 手术后复发性腰椎间盘 (PRLDH) 是腰椎间盘手术后的一种常见并发症.
  • 穿皮内镜转膜切除术 (PETD) 是一种微创手术技术.

研究的目的:

  • 评估PETD后对PRLDH的副脊髓肌肉的预测值.
  • 开发一种预测模型,用于识别PRLDH高风险患者.

主要方法:

  • 对接受PETD的232名患者的回顾性分析.
  • 拉索和多变量后勤回归用于识别风险因素.
  • 开发和验证一个Nomogram预测模型.
  • 使用ROC曲线下的面积 (AUC) 和校准曲线评估模型准确性.
  • 使用决策曲线分析 (DCA) 和临床影响曲线 (CIC) 评估的临床效用.

主要成果:

  • 糖尿病,Modic变化和ipsilesional多肌骨肌指数 (SMI) 被确定为PRLDH的独立预测因素 (P<0.05).
  • 诺莫格拉姆模型表现出高预测精度,AUC值为0.921 (训练) 和0.900 (验证).
  • 该模型显示了良好的校准和显著的临床净益在各种风险值.

结论:

  • 开发的Nomogram模型结合了副脊髓肌肉参数,有效地预测了PETD后的PRLDH风险.
  • 该工具有助于对接受PETD的患者进行个性化风险评估和临床决策.