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Updated: Jun 23, 2025

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
07:41

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators

Published on: February 20, 2018

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发现了小分子瓜尼利环酶B受体阳性全调节剂

Xiao Ma1, Satyamaheshwar Peddibhotla2, Ye Zheng1

  • 1Cardiorenal Research Laboratory, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN 55905, USA.

PNAS nexus
|June 19, 2024
PubMed
概括

研究人员发现了MCUF-42,这是一种新型小分子,增强了瓜尼利环酶B (GC-B) 受体通路. 这一发现为治疗心脏纤维化和心血管疾病 (CVD) 提供了新的治疗策略.

关键词:
cGMP的良好使用情况.瓜尼利环酶B受体是什么?小分子分子小分子

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