新型氨酸激酶2抑制剂用于治疗自身免疫和炎症性疾病
1Smith, Gambrell & Russell LLP, 1105 W. Peachtree Street NE, Suite 1000, Atlanta, Georgia 30309, United States.
新型氨酸激酶2抑制剂为自身免疫和炎症性疾病提供了新的治疗方法. 这些化合物及其制备方法是详细的,为治疗进步铺平了道路.
科学领域:
- 药用化学 医学化学
- 免疫学 免疫学 免疫学
- 药理学 药理学是指药理学的学科.
背景情况:
- 自身免疫和炎症性疾病代表着一个重要的未满足的医疗需求.
- 目前针对这些疾病的治疗方法通常在疗效或副作用方面存在局限性.
- 针对特定的信号通路,例如涉及氨酸激酶的信号通路,是一种有前途的治疗策略.
更多相关视频
07:42Assessment of Resistance to Tyrosine Kinase Inhibitors by an Interrogation of Signal Transduction Pathways by Antibody Arrays
Published on: September 19, 2018
08:49Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries
Published on: January 22, 2019
相关概念视频
Transducer Mechanism: Enzyme-Linked Receptors
Major types that are helpful drug targets include:
Drugs for Treatment of Crohn's Disease in IBD Using Biologic Agents: Anti-TNF
Tumor Immunotherapy
Treatment for Pulmonary Arterial Hypertension: Receptor Tyrosine Kinase Inhibitors and Calcium Channel Blockers
TKIs, such as imatinib (Gleevec), are particularly effective in tackling the growth and mitogenic factors that become upregulated in PAH patients. These factors contribute to the...
T Cell Types and Functions
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
Targeted Cancer Therapies
There are several types of targeted therapies against...
