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双抗血小板不响应:对克洛皮多格雷尔和提卡格雷勒的耐药性
Anna Luisa Kuhn1, Jasmeet Singh1, Ajit S Puri1
1Department of Radiology, Division of Neurointerventional Radiology, University of Massachusetts Chan Medical School, Worcester, MA, USA.
提卡格雷勒无反应是罕见的,但可能发生在接受神经干预手术的患者中. 通过血小板抑制测试来识别这些人对于预防严重并发症至关重要.
科学领域:
- 神经干预程序的神经干预程序
- 心血管医学 心血管医学
- 药理学 药理学是指药理学的学科.
背景情况:
- 双重抗血小板治疗 (阿司匹林和克洛皮多格雷尔) 是神经干预的标准,涉及支架或流量转移器.
- 很大一部分患者对克洛皮多格勒的治疗反应不足,需要使用替代性抗血小板药物.
- 提卡格勒勒提供了一个具有良好的特征的强效替代品,尽管不响应是可能的,虽然很少见.
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