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Updated: Jun 23, 2025

In Vivo Immunogenicity Screening of Tumor-Derived Extracellular Vesicles by Flow Cytometry of Splenic T Cells
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敏感化瘤免疫疗法:免疫性细胞死亡诱导纳米系统

Jianlan Peng1, Shiying Li2, Huihui Ti1,3

  • 1School of Chinese Materia Medica, Guangdong Pharmaceutical University, Guangzhou, People's Republic of China.

International journal of nanomedicine
|June 19, 2024
PubMed
概括

瘤免疫疗法由于瘤免疫性较低而面临挑战. 纳米材料可以诱导免疫细胞死亡 (ICD),增强抗瘤免疫力,并可能改善癌症治疗结果.

关键词:
污水堆 (DAMP) 是一种污水堆.在ICD的基础上,ICD是ICD.免疫性 免疫性 免疫性纳米系统纳米系统瘤免疫疗法 免疫疗法

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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Cytotoxic T cells are a vital component of the immune system. They have the remarkable ability to identify and target antigens on infected or abnormal cells. These antigens often originate from intracellular pathogens such as viruses or abnormal proteins cancer cells produce.
Immunological surveillance is the ability of immune cells to monitor and eliminate infected cells with intracellular pathogens, neoplastically transformed cells, and cells with non-self antigens. Cytotoxic T cells and NK...
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