计算机化认知训练对轻度认知障碍的老年人生物标志物反应的影响:一个范围审查
Hiroshi Hayashi1, Toshimasa Sone1, Kazuaki Iokawa1
1Department of Occupational Therapy Fukushima Medical University School of Health Sciences Fukushima Japan.
Health science reports
|June 19, 2024
概括
计算机认知训练 (CCT) 提高了老年轻度认知障碍 (MCI) 的大脑功能和结构,可能延迟痴呆症. 推个性化的CCT策略,以最大限度地提高效益.
科学领域:
- 神经科学是一个神经科学.
- 老年学是指老年学的学科.
- 认知心理学 认知心理学
背景情况:
- 轻度认知障碍 (MCI) 在老年人中普遍存在,并增加痴呆风险.
- 有限的研究存在于有效的干预措施及其对MCI的神经影响.
- 了解神经机制对于制定痴呆症预防策略至关重要.
研究的目的:
- 研究计算机化认知训练 (CCT) 对患有MCI的老年人的影响.
- 探索CCT对痴呆症预防的影响背后的神经机制.
- 为MCI提供未来干预工作的信息.
主要方法:
- 随机对照试验 (RCT) 的系统审查发表 2010-2023.
- 在PubMed,Scopus和CINAHL搜索了关于MCI,CCT和生物标志物结局的研究.
- 包括使用定量生物标志物评估的研究.
主要成果:
- CCT诱导的结构和功能大脑网络变化,包括默认模式网络.
- 脑电图和fNIRS显示,甲基节律和前额活动下降,与认知能力的改善相关.
- 结合CCT和体育炼产生了更大的大脑变化;基于VR的CCT改善了日常生活活动.
结论:
- 在患有MCI的老年人中,CCT促进了显著的功能和结构性大脑变化.
- 个性化的CCT干预和生物标志物评估对于个性化的痴呆症预防至关重要.
- 进一步的研究应该优化针对MCI患者的个性化CCT策略.
关键词:
生物标志物生物标志物大脑衍生的神经营养因子计算机化认知训练是计算机化的认知训练.电脑脑电图 (EEG) 是一种电脑电图.功能近红外光谱学近红外光谱学磁共振成像技术的使用轻度的认知障碍 轻度的认知障碍更多相关视频
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