在晚期癌症患者中,营养影响与抑郁症症状的关联
Koji Amano1, Satomi Okamura2, Yoshinobu Matsuda3
1Department of Supportive and Palliative Care, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-Ku, Osaka, 541-8567, Japan. kojiamano4813@gmail.com.
概括
晚期癌症患者经历了四种或更多的营养影响症状 (NIS),严重程度得分为4或更高,抑郁的可能性明显更高. 这突显了严重的NIS与息治疗中的抑郁症之间的联系.
科学领域:
- 在瘤学瘤学.
- 精神病学是一个精神病学.
- 临床营养学 临床营养学
背景情况:
- 晚期癌症患者经常经历营养影响症状 (NIS).
- 在这种患者群体中,抑郁情绪也很普遍.
- 尼斯和抑郁症之间的关系需要进一步调查.
研究的目的:
- 确定NIS的严重程度和数量与晚期癌症患者的抑郁症之间的关联.
- 为了确定与抑郁症状相关的特定NIS.
主要方法:
- 进行了对息治疗患者的二次分析.
- 饮食摄入量和19个NIS被评估,使用10分级.
- 根据PHQ-9分数,患者被分为抑郁和非抑郁组;用于计算调整的几率比率 (OR) 和95%置信区间 (CI) 的逻辑回归分析.
主要成果:
- 抑郁症的患病率为34.2% (225名参与者中有77名).
- 与非抑郁组相比,抑郁组的患者饮食摄入量较低,NIS数量较多 (得分≥4) (p < 0.001).
- 拥有4-6个NIS (OR = 10.76) 或7+个NIS (OR = 17.02) 的得分≥4显著增加了抑郁症的几率.
结论:
- 具有4分或更高分数的4个或更多NIS的存在与晚期癌症患者的抑郁症有显著联系.
- 这些发现强调了监测和管理NIS的重要性,以潜在地缓解该群体的抑郁症状.
相关概念视频
Psychoneuroimmunology: Diabetes and Cancer
27
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
27
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
331
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
331
Cancer Prevention
6.1K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
6.1K
Anorexia Nervosa
59
Anorexia nervosa is a complex and severe eating disorder characterized by an intense fear of weight gain, an unrelenting pursuit of thinness, and a distorted body image. It often leads to dangerously low body weight relative to an individual's age and height. This disorder is marked by significant physical and psychological consequences, making it one of the most life-threatening psychiatric illnesses.
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
59
Taste Buds and Receptors
1.9K
Gustation, or the sense of taste, is intrinsically linked to the anatomical structures located on the tongue. This organ's surface, along with the entirety of the oral cavity, is adorned with stratified squamous epithelium. Evident on the tongue are elevated structures known as papillae (singular = papilla), which house the mechanisms for the transduction of gustatory stimuli. Four distinct types of papillae exist, each identified by their unique morphological attributes: the circumvallate,...
1.9K
Cancer Survival Analysis
342
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
342


