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弹性和脆弱性的集群:在患有扩散低度质瘤的患者中执行功能,应对和精神困扰

Floor Gelmers^1,2,3, Marieke E Timmerman⁴, Femke F Siebenga^5,6

¹Department of Clinical Neuropsychology, University of Groningen, University Medical Center Groningen, P.O. Box 30.001, Groningen, AB51, 9700RB, The Netherlands. f.gelmers@umcg.nl.

Journal of neuro-oncology

|June 19, 2024

概括

患有扩散性低度质瘤 (dLGG) 的患者可能会经历痛苦. 不适应性应对,而不是执行功能缺陷,与DLGG患者的精神困扰程度更高有关.

科学领域:

神经瘤学神经瘤学
大脑瘤对心理的影响
认知神经科学是一种认知神经科学.

背景情况:

扩散性低度质瘤 (dLGG) 通常发生在额叶,可能会影响执行功能 (EF).
对DLGG的诊断和治疗可能会导致严重的情绪压力.
损坏的EF可能会阻碍适应性应对机制,导致精神痛苦增加.

研究的目的:

在DLGG患者中识别执行功能 (EF),应对策略和精神困扰的不同形状.
确定与每个已识别的配置文件相关的特征.
调查EF,应对能力和精神困扰之间的关系,在这个患者群体.

主要方法:

隐性概况分析 (LPA) 用于根据EF,应对能力和心理困扰来对患者进行分类.
该研究包括了151名被诊断为DLGG的患者.
分析了人口统计,瘤和放射学数据,以表征识别的个人资料.

主要成果:

出现了四种不同的患者概况:整体良好功能 (25%),糟糕的EF/良好的心理社会 (32%),良好的EF/糟糕的心理社会 (18%) 和整体糟糕的功能 (25%).
个人资料特征包括教育水平,血管大脑损伤,年龄和瘤体积.
适应不良的应对策略与更高的精神痛苦有显著的关联,而EF损伤并不是应对或痛苦水平的区分因素.

结论:

确定了四个独特的患者集群,具有不同的功能水平和特征.
执行职能缺陷并没有阻碍采取积极应对策略.
不适应性应对,而不是EF损伤,与DLGG患者的精神痛苦增加直接相关.

关键词:

焦虑焦虑是一种焦虑.应对情况应对情况抑郁症抑郁症抑郁症执行职能执行职能执行职能低度结质瘤是低度的结质瘤.

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