对于患前列腺癌风险较高的人士的查指南
Justin Lorentz1, Julia Woollcombe1, Andrew Loblaw1
1Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada; Sunnybrook Health Sciences Centre, Toronto, ON, Canada.
概括
定义前列腺癌风险在指南中不一致. 学术中心的患者登记册可以帮助澄清风险组和终身风险,以改善前列腺癌查.
科学领域:
- 在瘤学瘤学.
- 遗传学 遗传学 是一个
- 公共卫生 公共卫生
背景情况:
- 前列腺癌 (PCa) 风险分层在目前的指南中缺乏一致的定义.
- 现有的NCCN和AUA的指导方针为查启动和方法提供了不同的建议.
研究的目的:
- 为了突出定义患前列腺癌风险增加的个体的不一致性.
- 强调PCa风险评估和查协议中需要采用标准化的方法.
主要方法:
- 审查目前国家和国际指导方针前列腺癌风险识别.
- 分析NCCN和美国泌尿器官学会 (AUA) 的查建议.
- 建议建立患者登记册,以促进PCa风险的持续研究.
主要成果:
- 在定义前列腺癌高风险人群方面存在显著的变化.
- 查启动 (例如40岁) 和方法 (PSA,DRE) 的建议各不相同.
- 生殖系突变,家族史和祖先是PCa风险评估的关键因素.
结论:
- 标准化前列腺癌风险增加的定义对于公平的查至关重要.
- 患者登记册对于进一步了解PCa终身风险至关重要.
- 需要进一步的研究来完善PCa风险分层和选策略.
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