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Updated: Jun 23, 2025

Optimization of Synthetic Proteins: Identification of Interpositional Dependencies Indicating Structurally and/or Functionally Linked Residues
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Optimization of Synthetic Proteins: Identification of Interpositional Dependencies Indicating Structurally and/or Functionally Linked Residues

Published on: July 14, 2015

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在原型的非核糖体合成酶中,模块间识别的特异性取决于适应器域

Megha N Karanth1,2, John P Kirkpatrick2,3,4, Joern Krausze2

  • 1Laboratory of Integrative Structural Biology, Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK.

Science advances
|June 19, 2024
PubMed
概括

非核糖体合成酶 (NRPS) 产生各种生物活性化合物. 研究人员在托马米NRPS中发现了一个新的适应器域,揭示了它如何控制合成生物学应用的载体蛋白招募.

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