巴西结核病发病率:2001年至2021年间的时间序列分析和到2030年的预测
Marcus Tolentino Silva1, Taís Freire Galvão2
1Universidade de Brasília, School of Health Sciences, Public Health Department - Brasília (DF), Brazil.
概括
巴西的结核病发病率在2014年之前一直在下降,然后增加,而大流行导致数据异常. 预测显示,到2030年,发病率将恢复到2000年代的水平,强调需要加强预防和控制战略.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 时间序列分析 时间序列分析
背景情况:
- 结核病 (TB) 仍然是一个重大的全球卫生挑战.
- 监测结核病发病趋势对于有效的控制策略至关重要.
- 巴西面临着不断波动的结核病发病率,需要进行更新的评估.
研究的目的:
- 分析2001年至2022年巴西结核病发病率.
- 预测到2030年巴西每月的结核病发病率.
- 为与可持续发展目标 (SDGs) 保持一致的公共卫生干预提供信息.
主要方法:
- 采用时间序列研究设计,使用来自巴西可报告疾病信息系统的每月结核病数据.
- 使用细分线性回归来确定结核病发病率的趋势变化 (2001-2022年).
- 应用季节性自回归集成移动平均 (Sarima) 模型用于每月结核病发病率预测 (2023-2030年).
主要成果:
- 从2001年到2014年,结核病发病率下降,随后从2015年开始大幅增加.
- 2020年4月,COVID-19大流行导致报告病例急剧下降,随后出现加速增长.
- 预计2030年结核病发病率为4.64例/月/100万人口,与2000年代初的水平相似.
- 在排除大流行期间时,Sarima模型表现出4.1%的错误率的稳定性.
结论:
- 从2015年开始,结核病减少趋势的逆转,与经济危机和流行病相吻合,强调了复杂的影响因素.
- 萨里马模型是流行病监测和预测结核病发病率的宝贵工具.
- 增加对结核病预防和控制的投资对于实现减少结核病的可持续发展目标至关重要.
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