登革热负担和影响洪都拉斯严重性的因素:描述性和分析性研究
Melba Zúniga-Gutiérrez1, Marlon Meléndez2, Saroni Shadai Rodríguez Montoya2
1Universidad Nacional Autónoma de Honduras, Research Institute in Medical Sciences and Right to Health, Epidemiology Postgraduate Program Tegucigalpa, Honduras.
Revista da Sociedade Brasileira de Medicina Tropical
|June 19, 2024
概括
洪都拉斯的登革热严重程度与年轻年龄组 (19岁以下) 以及拉巴斯和科班等特定地区有关. 这项研究分析了14000多例病例,以确定严重登革热结果的关键风险因素.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
背景情况:
- 登革热在洪都拉斯构成了重大公共卫生挑战,导致大量的发病率和死亡率.
- 了解登革热的流行病学模式和风险因素对于有效的疾病控制至关重要.
研究的目的:
- 分析洪都拉斯2016-2022年登革热病例数据.
- 确定与登革热严重程度相关的人口和地理因素.
主要方法:
- 一项具有分析组成部分的描述性研究,利用来自国家病毒学实验室 (2016-2022) 的数据.
- 使用顺序后勤回归来分类登革热病例:没有警告信号的登革热 (DWOS),有警告信号的登革热 (DWS) 和严重的登革热 (SD).
主要成果:
- 在14687例登革热病例中,50.1%为DWOS,36.5%为DWS,13.4%为SD.
- 年龄组1-19岁,男性性别和居住在拉巴斯,科班或瓦莱省的住所与增加DWS和SD风险显著相关.
- 为这些关联计算了特定的几率比率 (OR) 和95%置信区间 (CI).
结论:
- 登革热在洪都拉斯表现出流行性行为,在2015年和2019年观察到流行病峰值.
- 预测严重登革热的关键因素包括19岁以下的年龄,男性性别和位于拉巴斯,科班或瓦莱的地理位置.
- 调查结果强调,需要针对高风险人群和地区进行有针对性的干预.
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