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Updated: Jun 23, 2025

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由于Fut2缺乏,慢性结肠炎会通过2-oxindole-AHR介导的cGAS-STING通路恶化

Gaichao Hong1, Yajuan Zhao2, Qingyuan Li1

  • 1Guangdong Provincial Key Laboratory of Gastroenterology, Department of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.

International immunopharmacology
|June 19, 2024
PubMed
概括

失去了fucosyltransferase 2 (Fut2) 通过激活cGAS-STING通路,使肠道炎症恶化. 然而,微生物代谢物2-oxindole可以抑制这种途径,并改善Fut2缺乏小鼠的结肠炎.

关键词:
这样,二氧化二氧化二氧化二氧化二氧化.美国人权委员会 (AHR)慢性结肠炎是一种慢性结肠炎.未来的时间 未来的时间cGAS-STING 的使用情况.

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