长期阿片类药物使用者中 gabapentinoid 使用模式
Jordan Westra1, Mukaila Raji2, Jacques Baillargeon3
1Department of Biostatistics and Data Science, School of Public and Population Health, University of Texas Medical Branch, Galveston, TX, USA.
Preventive medicine
|June 19, 2024
概括
长期使用阿片类药物的人群中的 gabapentinoid 使用显著增加,西班牙裔种族和特定的疼痛类型与更高的处方率相关. 高龄和因年龄而产生的医疗保险权利与使用量减少有关,突出显示了处方差异.
科学领域:
- 疼痛管理 疼痛管理
- 药物监督 药物监督 药物监督
- 医疗保健服务研究 医疗服务研究
背景情况:
- gabapentinoids 经常被处方用于治疗疼痛.
- 了解处方模式对于优化患者护理和安全至关重要.
- 长期使用阿片类药物的人群是研究 gabapentinoid 用途的关键人群.
研究的目的:
- 检查长期阿片类药物使用者中 gabapentinoid 使用的趋势和预测因素.
- 为了确定与 gabapentinoid 处方相关的人口和临床因素.
- 为临床实践提供信息,并指导未来关于 gabapentinoid 疗效和安全性的研究.
主要方法:
- 2014-2020年国家医疗保险样本的分析.
- 包括长期使用阿片类药物且之前没有使用过 gabapentinoid 的患者.
- 后勤回归来评估与年龄,人口统计,健康状况和阿片类药物使用的关联.
主要成果:
- 在长期使用阿片类药物者中, gabapentinoid 的使用量从 12.6% (2014) 增加到 16.8% (2019).
- 西班牙裔种族,背部疼痛,神经疼痛和较高的阿片类药物MME与增加的加巴类药物使用有关.
- 年龄较大和因年龄而导致的医疗保险权利与 gabapentinoid 使用量减少有关.
结论:
- 根据社会人口统计和保险情况, gabapentinoid 的处方有所不同,这表明潜在的差异.
- 患者和提供者之间需要共享决策,以讨论疼痛治疗的安全性和有效性.
- 对加巴类药物在不同人群中的慢性非癌症疼痛的比较有效性和安全性进行进一步的研究是有必要的.
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