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Updated: Jun 23, 2025

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乌比基化参与PKC介导的细胞表面Kv1.5通道的降解

Ananya Chakraborty1, Amanda Paynter1, Mark Szendrey1

  • 1Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada.

The Journal of biological chemistry
|June 19, 2024
PubMed
概括

蛋白激酶C (PKC) 的激活触发了Kv1.5通道通过ubiquitination降解. 特定的C端残留物,特别是Cys604,对于这个过程至关重要,为Kv1.5调节提供了洞察力.

关键词:
补丁紧固件 补丁紧固件蛋白质激酶 C 的蛋白质激酶 C.无处不在的化电压接入通道的通道

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