英国新生儿口腔实践:一个人口研究
Graciaa Singhal1, Rema Ramakrishnan2, Raph Goldacre3
1Neonatal Medicine, School of Public Health, Imperial College London, London, UK.
概括
接受口腔外科手术的英国新生儿的数量足以进行临床试验. 口腔闭塞通常发生在两个月左右,受婴儿的稳定性,体重和并发症的影响,表明实践优化的空间.
科学领域:
- 儿科手术 儿科手术
- 新生儿护理 新生儿护理
- 临床试验可行性临床试验可行性
背景情况:
- 新生儿口腔关闭的最佳时间仍未确定.
- 之前曾有人呼吁对早期和晚期口腔闭塞进行比较试验.
- 试验可行性取决于符合条件的患者群体和利益相关者的接受.
研究的目的:
- 评估英国新生儿口腔外科手术当前的做法.
- 为了描述经历了口腔形成和关闭的新生儿.
- 为了确定临床试验的可行性,关于口腔闭塞时间的临床试验.
主要方法:
- 使用三个英国国家数据库 (NNRD,BAPS-CASS,HES-APC) 的回顾性队列研究.
- 纳入标准:接受口腔外科手术的新生儿 (不包括门形和希尔施普朗格病).
- 分析了患者特征,静脉管持续时间和关闭时间指标 (2011-2019) 的数据.
主要成果:
- 在数据库中发现了1830-2477名新生儿的大量队列.
- 静脉静脉的平均持续时间从57天到78天不等.
- 早期关闭 (<9周) 与较少的早产婴儿,更高的出生体重和增加的静脉口腔并发症有关.
结论:
- 足够多的英国新生儿经历了口腔形成,以支持临床试验.
- 口腔闭塞通常在形成后2个月左右进行.
- 临床稳定性,妊娠年龄,体重和静脉关口并发症影响关闭时间,建议优化机会.
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