在霍奇金淋巴瘤中使用当代放射治疗
Omran Saifi1, Bradford S Hoppe1
1Department of Radiation Oncology, Mayo Clinic, Jacksonville, FL.
Seminars in hematology
|June 19, 2024
概括
放射治疗对于管理霍奇金淋巴瘤至关重要,最近的进展提高了疗效,降低了毒性. 本综述考察了辐射技术,以优化治疗和尽量减少副作用.
科学领域:
- 在瘤学瘤学.
- 辐射瘤学 辐射瘤学
背景情况:
- 放射治疗是霍奇金淋巴瘤联合治疗方式的关键组成部分.
- 它对于早期疾病和管理晚期局部复发风险至关重要.
研究的目的:
- 审查霍奇金淋巴瘤放射治疗的当前指示和进展.
- 专注于提高治疗效率,同时尽量减少与辐射相关的毒性.
主要方法:
- 对霍奇金淋巴瘤的放射治疗技术的综合文献综述.
- 检查强度调节辐射疗法 (IMRT),体积调节弧线疗法 (VMAT) 和质子疗法.
- 对最佳剂量选择和治疗规划策略的分析.
主要成果:
- 诊断成像技术的进步使得辐射场的大小和剂量减少.
- 辐射技术的进步导致毒性降低,但不影响治疗的有效性.
结论:
- 优化霍奇金淋巴瘤的放射治疗包括平衡疾病控制与减少长期副作用.
- 对IMRT,VMAT和质子疗法等先进技术的进一步研究对于改善患者的治疗结果至关重要.
相关概念视频
Cancer Therapies
7.6K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
7.6K
Tumor Immunotherapy
511
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
511
Targeted Cancer Therapies
7.5K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.5K
Cancer Vaccines
352
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
352
Bone Marrow Sampling and Transplants
324
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
324


