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Updated: Jun 23, 2025

In Vitro Assay for Studying the Aggregation of Tau Protein and Drug Screening
09:49

In Vitro Assay for Studying the Aggregation of Tau Protein and Drug Screening

Published on: November 20, 2018

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在R3陶中的氨酸调节血红素结合和活性

Chiara Bacchella1, Teresa Benedetta Guerriere1,2, Enrico Monzani1

  • 1Dipartimento di Chimica, Università di Pavia, Via Taramelli 12, Pavia 27100, Italy.

Inorganic chemistry
|June 19, 2024
PubMed
概括

这是一种tau蛋白质.

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Allosteric Proteins-ATCase01:19

Allosteric Proteins-ATCase

Binding sites linkages can regulate a protein's function.  For example, enzyme activity is often regulated through a feedback mechanism where the end product of the biochemical process serves as an inhibitor.
Aspartate transcarbamoylase (ATCase) is a cytosolic enzyme that catalyzes the condensation of L-aspartate and carbamoyl phosphate to  N-carbamoyl-L-aspartate. This reaction is the first step in pyrimidine biosynthesis. UTP and CTP, the end products of the pyrimidine synthesis...
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