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Updated: Jun 23, 2025

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice
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在慢性病和功能方面,通过将多基蛋白与转录基因组集成来确定新的治疗点

Shucheng Si1,2, Hongyan Liu1,2, Lu Xu1,2

  • 1Research Center of Clinical Epidemiology, Peking University Third Hospital, Beijing, 100191, China.

Genome medicine
|June 19, 2024
PubMed
概括

这项研究通过整合蛋白质组和转录组数据,确定了32种与慢性病 (CKD) 和功能相关的蛋白质. 这些发现为CKD和相关疾病提供了潜在的新治疗点.

关键词:
慢性脏疾病 慢性脏疾病功能 功能 功能门德尔的随机化蛋白质组是蛋白质组的组成部分.治疗目标 治疗目标转录组 转录组就是一个转录组.

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Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
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