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用立体辐射疗法治疗超结瘤的治疗方法

Antonio Pontoriero¹, Paola Critelli¹, Marco Zeppieri²

¹Radiation Oncology Unit, Department of Biomedical, Dental Science and Morphological and Functional Images, University of Messina, Messina 98125, Italy.

World journal of clinical cases

|June 20, 2024

概括

分割式立体辐射疗法 (FSRT) 对不可切除的偏角质瘤 (PG) 显示出有希望的结果. 这种治疗为患有这些罕见瘤的患者提供了有效的局部控制和手术的安全替代方案.

科学领域:

神经瘤学神经瘤学
辐射瘤学辐射瘤学
内分泌学在内分泌学.

背景情况:

帕拉根瘤 (PG) 是一种罕见的,生长缓慢的神经内分泌瘤.
目前的治疗方法包括手术切除 (SR),放射治疗 (RT) 和观察.
不切割的PG (uPG) 带来了独特的管理挑战.

研究的目的:

评估针对不可切除的PG (uPG) 的专用分离立体 RT (FSRT) 的疗效和安全性.
评估FSRT治疗的uPG患者的局部控制率和与治疗相关的毒性.

主要方法:

使用CyberKnife系统使用FSRT治疗的6名uPG患者的回顾性分析.
患者在医学上是不可操作的或拒绝了SR.
治疗后评估了毒性和初始疗效.

主要成果:

在6名患者中,有5名患者实现了100%的5年整体和无进展生存.
在FSRT期间和之后观察到微不足道的毒性.
大多数患者经历了稳定的症状,其中一个患有脊髓转移.

结论:

对于不可切除的PG,FSRT似乎是一种有效和安全的治疗选择.
这项初步研究表明,FSRT可以作为选择uPG患者的SR的可行替代方案.

关键词:

这是一把网络刀.分割式立体性辐射疗法分割式立体性辐射疗法.转移转移转移转移神经外科神经外科无法切除的双角瘤.

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