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Updated: Jun 23, 2025

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对SHANK1 PDZ域与内部SLiM之间相互作用的生物物理和结构分析

Yue Li1,2, Chi H Trinh2,3, Amanda Acevedo-Jake4

  • 1School of Chemistry, University of Leeds, Woodhouse Lane, Leeds LS2 9JT, U.K.

The Biochemical journal
|June 20, 2024
PubMed
概括

研究人员在EESTSFQGP序列中发现了一种新的内部PDZ结合基因 (PBM). 这种短线性图案 (SLiM) 显示出与SHANK1 PDZ域的强有力的结合,提供了新的治疗向可能性.

关键词:
这里是PDZ域名.酸相互作用的图案.蛋白质蛋白质相互作用

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