在生物修饰性大动脉置换后的亚临床叶血栓形成
Carlos Giuliani1, Antonela Zanuttini, Erwan Salaun
1Institut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, Québec, Québec, Canada.
Current opinion in cardiology
|June 20, 2024
概括
亚临床传单血栓症 (SLT) 影响了10-20%的透气导管大动脉置换 (TAVR) 患者和5-15%的外科大动脉置换 (SAVR) 患者. 虽然SLT通常会自发消失,但可能会增加中风风险和冲击的耐用性.
科学领域:
- 心脏病学 心脏病学
- 生物医学工程 生物医学工程
- 放射学 放射学是一门学科.
背景情况:
- 亚临床传单血栓 (SLT) 是一种以大动脉传单上的血栓为特征的疾病,通常通过多探测器计算机断层扫描 (MDCT) 识别为低衰减传单加厚 (HALT).
- 通过导管大动脉置换 (TAVR) 和生物手术大动脉置换 (SAVR) 后,SLT可能发生.
研究的目的:
- 审查关于SLT在TAVR和SAVR之后的发病率,诊断,临床影响和管理的当前知识.
主要方法:
- 在TAVR和SAVR之后,对SLT现有文献的审查.
- 对诊断方式的分析,包括心声回声和MDCT.
- 评估临床结果和管理策略.
主要成果:
- 在TAVR后,SLT的发病率为10-20%,在SAVR后为5-15%.
- 大约50%的SLT病例自发回归;用维生素K对抗剂的口服抗凝药是有效的.
- SLT与中风风险的轻微增加和潜在的加速结构膜恶化有关,但与死亡率无关.
结论:
- 在TAVR和SAVR之后,SLT是一个常见的偶然发现.
- 管理包括监测和考虑抗凝剂,这可能会影响门的耐用性.
- SLT影响血栓栓塞风险和长期门性能.
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