在上胃肠道中 Sarcina ventriculi 的临床病理学特征
Mark Ettel1, Zhenjian Cai2,3, Xiaoyan Liao1
1Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, USA.
International journal of surgical pathology
|June 20, 2024
概括
在上部的胃肠道中很少发现 Sarcina ventriculi (SV). 这项研究强调了它与糖尿病和胃衰竭等疾病的关联,这可能导致严重的结果,包括急性病例的死亡.
科学领域:
- 胃肠病学 胃肠病学
- 微生物学 微生物学
- 病理学 病理学 病理学
背景情况:
- 腹腔 (Sarcina ventriculi,SV) 是一种罕见的细菌,存在于胃肠道上部.
- 脊髓炎已与各种临床表现有关,需要对其临床病理特征有更深入的了解.
研究的目的:
- 在胃肠道中描述Sarcina ventriculi的临床病理特征.
- 为了确定与SV感染相关的常见并发症和内镜检查结果.
主要方法:
- 对17个样本 (3个胃切除术,14个活检) 进行了回顾性分析,并对SV进行了组织学诊断.
- 对患者人口统计,临床表现,内镜检查结果,组织学严重程度和并发症的审查.
主要成果:
- 主要在胃部发现 (82%),偶尔在食道和十二指肠中发现.
- 常见的并发症包括糖尿病 (59%) 和胃/输液阻塞 (59%),通常与保留的食物残留物有关.
- 组织学发现范围从轻微的改变 (71%) 到严重的侵蚀,,亡或穿孔 (29%).
- 与SV相关的急性质性胃炎导致18%的胃切除术后患者死亡.
结论:
- 这一病例系列是最大的报告,描述了在SV感染中组织学严重程度的范围.
- 糖尿病和胃衰竭是常见的发现,可能会促进 SV 的生长和致病性.
- 脊髓炎感染可以呈现出各种胃肠道症状和严重程度的范围,急性病例具有显著的风险.
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