穿透弹性头骨创伤中的凝血病:一个7年的经验
Ahmad Alhourani1, Tyler L Stephenson1, Elizabeth M Bridwell1
1Department of Neurosurgery, University of Louisville, Louisville , Kentucky , USA.
Neurosurgery
|June 20, 2024
概括
几乎一半的穿透弹道头脑创伤 (PBCT) 患者患有凝血病,这是一种与严重伤害和较高死亡率相关的疾病. 血栓形成显微镜可以改善凝血病的检测,并指导这些关键病例的治疗.
科学领域:
- 创伤外科 手术 创伤外科
- 紧急医疗 紧急医疗
- 血液学 血液学 血液学
背景情况:
- 穿透弹道头脑创伤 (PBCT) 与死亡率高于重创伤有关.
- 凝血病是PBCT患者死亡率的重要预测因素.
- 了解凝血病发病率和风险因素对于改善结局至关重要.
研究的目的:
- 确定PBCT中凝血病的发病率和风险因素.
- 为了评估在PBCT患者中甘酸的有效性.
- 为了探索血栓等学在识别凝血病的实用性.
主要方法:
- 来自1级创伤中心的270名PBCT患者 (2016-2023) 的回顾性分析.
- 评估凝血病的发展及其与损伤模式和实验室值的相关性.
- 对特兰克萨姆酸的使用和使用血栓凝结术的评估.
主要成果:
- 47%的PBCT患者在呈现时发生了凝血病.
- 凝血病与更严重的损伤模式 (双半球,透视) 和更大的基础缺陷有关.
- 特兰胺酸没有影响凝血病的发展;血栓凝结显微镜确定了额外的凝血病患者.
结论:
- 凝血病在PBCT中非常普遍,并且可能是持久的.
- 与常规测试相比,血栓等级图提供了对凝血病检测的更高灵敏度.
- 对动脉血液气体的显著基础缺陷是PBCT中凝血病的危险因素.
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