在儿童中扩大登革热综合征的临床特征
Vidushi Mahajan1, Jasmine Singh, Vishal Guglani
1From the Department of Pediatrics, Government Medical College and Hospital, Chandigarh, India.
The Pediatric infectious disease journal
|June 20, 2024
概括
扩大型登革热综合征 (EDS) 影响了18.5%的登革热患者住院治疗的儿童. 神经和胃肠道问题很常见,EDS与更长的住院时间有关.
科学领域:
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
- 病毒学 病毒学
背景情况:
- 登革热是全球重要的健康问题,特别是在儿童群体中.
- 扩大型登革热综合征 (EDS) 涵盖了除了经典登革热出血热之外的严重登革热表现.
- 了解儿童EDS的临床特征和结果对于及时诊断和管理至关重要.
研究的目的:
- 研究儿童扩散登革热综合征 (EDS) 的临床特征和结果.
- 为了确定儿童登革热患者中EDS的患病率.
- 为了比较患有EDS和没有EDS的儿童的临床和实验室资料.
主要方法:
- 对患有登革热的儿童 (1个月至18岁) 的回顾性队列研究.
- 登革热的诊断通过NS1抗原和/或IgM阳性得到证实.
- 基于世界卫生组织修订的指导方针 (2011年) 的EDS识别.
主要成果:
- 在178名登革热儿童中,有18.5%患有EDS.
- 神经系统参与 (脑病变,,脑炎) 是最常见的 (49%),其次是胃肠道 (30%) 和脏 (21%) 症状.
- 患有EDS的儿童表现出贫血,白细胞病,电解质失衡,肝酶升高,死亡率高,住院时间长.
结论:
- 扩大型登革热综合征 (EDS) 在患有登革热的住院儿童中患病率很高.
- 神经,和胃肠系统经常参与儿科EDS.
- EDS与较差的结果有关,包括长时间住院治疗和增加死亡率的趋势.
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