结构和功能连接的关联与前带带状突变异性
Luke Harper1, Olof Strandberg2, Nicola Spotorno2
1Clinical Memory Research Unit, Department of Clinical Sciences, Medical Sciences, Neuroscience, Lund University, Sölvegatan 19, 22100, Lund, Sweden. l.harper@doctors.org.uk.
Brain structure & function
|June 20, 2024
概括
在健康的成年人中,左侧状的存在与大脑连接的改变有关. 这种硫化会影响大脑中的结构和功能连接.
科学领域:
- 神经科学是一个神经科学.
- 人类解剖学 人类解剖学
- 大脑的连接性 大脑的连接性
背景情况:
- 硫化,具体来说是前带带状前带状的发展,发生在孕期晚期,影响认知功能.
- 大脑结构的变化,例如状的存在或不存在,可能会对神经疾病产生影响.
研究的目的:
- 为了研究状的存在对健康成年人的结构和功能大脑连接的影响.
- 探索如何ipsilateral paracingulate sulcal存在影响分数异构性,辐射扩散性和通道体积.
- 检查休息状态功能连接模式的差异,与状的存在相关.
主要方法:
- 横截面研究分析无任务静止状态功能连接和扩散权重成像数据.
- 队列包括129名60岁以下的健康成年人.
- 分析的重点是左侧垂突存在与特定的大脑连接指标之间的关联.
主要成果:
- 左侧状状的存在与左侧带束和周膝/背部段的分数异质性降低相关,表明结构组织不那么连贯.
- 观察到左侧周围牙区域的辐射扩散度和通道体积增加,左侧有状的存在,这表明U纤维的密度更高.
- 缺少左侧垂突的个体表现出更大的网络分散,其特点是显著的前部功能连接组件.
结论:
- 在健康的成年人中,左侧状的存在与独特的局部结构和功能连接模式有关.
- 这些变化可能源于使用短联接纤维的本地网络.
- 这些发现突出了大脑硫化和连接之间的新联系,这与理解神经变异有关.
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