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组织损伤和再生中的空间代谢学

Rosalie Gj Rietjens1, Gangqi Wang1, Bernard M van den Berg1

  • 1Department of Internal Medicine (Nephrology) & Einthoven Laboratory of Vascular and Regenerative Medicine & The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden University Medical Center, Leiden, The Netherlands.

Current opinion in genetics & development
|June 20, 2024
PubMed
概括

细胞代谢和代谢物交换对于组织修复和平衡至关重要. 先进的质谱成像技术有助于理解这些代谢过程,有助于组织修复和治疗策略.

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Regeneration and repair processes are critical in healing damages caused by injury, disease, and aging. In regeneration, the damaged tissue is entirely replaced with new growth that restores the original architecture and function. In contrast, tissue repair usually results in a fixed tissue architecture involving scar formation. Scars generally do not reestablish tissue function and may also exhibit structural abnormalities at the injury site.
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