相关实验视频

Updated: Jun 23, 2025

Author Spotlight: Combining Proximity Ligand Assay with Gamma-H2AX Staining to Characterize Protein Interactions in DNA Damage Response
09:39

Author Spotlight: Combining Proximity Ligand Assay with Gamma-H2AX Staining to Characterize Protein Interactions in DNA Damage Response

Published on: August 2, 2024

465

通过KBM与KU80之间的相互作用促进了CHO细胞对DNA复制应激的细胞抵抗力

Sophie E Wells1, Keith W Caldecott1

  • 1Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Science Park Road, Falmer, Brighton BN1 9RQ, UK.

DNA repair
|June 20, 2024
PubMed
概括

Ku异构体 (KU70/80) 使用其Ku结合基因 (KBM) 与DNA修复蛋白相互作用. 这种相互作用对抗DNA复制压力至关重要,特别是涉及维纳蛋白 (WRN).

关键词:
这就是DNA-PKK.双链断裂是双链断裂的原因之一.在这里,你会看到K.K.K.KU 绑定图案 KU 绑定图案尼希耶 (NHEJ) 是一个复制应激是复制应激的一种.

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