微塑料对脏的影响:叙述性回顾
Rodrigo Bueno de Oliveira1, Lauter E Pelepenko2, Daniela A Masaro1
1Internal Medicine Department, Nephrology Division, Laboratory for Evaluation of Mineral and Bone Disorders in Nephrology (LEMON), University of Campinas (UNICAMP), School of Medical Sciences, Campinas - São Paulo, Brazil.
Kidney international
|June 20, 2024
概括
微塑料 (MP) 和纳米塑料是普遍存在的环境污染物. 本综述探讨了它们的检测,生物效应和人类病中的潜在作用,强调了进一步研究的必要性.
科学领域:
- 环境科学 环境科学
- 毒理学 毒理学 毒理学
- 腎臟病學 (nephrology) 是一種醫學.
背景情况:
- 微塑料 (MP) 和纳米塑料是随处可见的合成颗粒 (<5毫米和<1微米),由塑料降解产生的.
- 这些颗粒污染了水,空气,食物和土壤,由于有记录的有害生物影响,造成了全球健康问题.
- 已在人体组织和液体中检测到MPs,包括脏,这表明潜在的暴露途径和积累.
研究的目的:
- 审查MP生成,分析识别方法和已知的毒理影响.
- 批判性地分析实验和临床研究,调查MPs在病中的作用.
- 为了突出慢性病中MP积累的潜力.
主要方法:
- 关于微塑料产生,检测和生物效应的科学研究的文献综述.
- 对实验和临床研究的批判性分析,将MP与功能和疾病联系起来.
- 综合目前关于MP存在和影响脏组织的证据.
主要成果:
- MPs分布广泛,可以通过摄入,吸入或皮肤接触进入人体.
- 生物组织中MPs的积累与炎症,氧化应激和器官功能障碍有关.
- 有证据表明,国会议员与人类脏疾病有关,但需要进一步调查.
结论:
- 国会议员代表着一个重要的环境和健康挑战,对脏健康有潜在的影响.
- 进一步的研究至关重要,以阐明MP在人类脏中的毒性机制及其在疾病发病过程中的作用.
- 在慢性病患者中调查MP积累是有必要的.
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