使CRISPR-Cas.

Rao Song1, Zhongyi Chen2, Hongtao Xiao1

  • 1Department of Pharmacy, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, Affiliated Cancer Hospital of University of Electronic Science and Technology of China, Chengdu 610041, China.

概括

克里斯普尔-卡斯系统为分子诊断提供了一个有希望的替代方案,可以在没有昂贵的设备的情况下快速和灵敏地检测疾病. 本次审查强调了其克服当前诊断方法局限性的潜力.

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Bacteria and archaea are susceptible to viral infections just like eukaryotes; therefore, they have developed a unique adaptive immune system to protect themselves. Clustered regularly interspaced short palindromic repeats and CRISPR-associated proteins (CRISPR-Cas) are present in more than 45% of known bacteria and 90% of known archaea.
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