相关实验视频

Updated: Jun 23, 2025

Quantifying Subcellular Ubiquitin-proteasome Activity in the Rodent Brain
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相互关联的命运:乌比基蛋白酶和自系统如何支神经认知结果

Xin Yang1, Julia Duckhorn1, John Marshall1

  • 1Department of Molecular Biology, Cell Biology and Biochemistry, Center for Translational Neuroscience, Carney Institute for Brain Science, Brown University, Providence, RI, United States.

Experimental neurology
|June 20, 2024
PubMed
概括

像UBE3A一样,E3泛素连接酶对于维持蛋白质平衡和认知功能至关重要. 失去UBE3A功能会破坏蛋白质稳定,导致神经发育障碍,如安吉尔曼综合征.

关键词:
安吉尔曼综合征是什么意思自自是一种自的过程.E3 无处不在的合酶突触的功能 突触的功能乌比基-蛋白酶体系统 (UPS) 是一种乌比奎丁-蛋白质结合酶E3A (UBE3A) 的使用

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