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Updated: Jun 23, 2025

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循环驱动的组织特异性在热量受限养条件下受到限制

Renrui Chen1, Ziang Zhang1, Junjie Ma1

  • 1CAS Key Laboratory of Computational Biology, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, 200031, China.

Communications biology
|June 20, 2024
PubMed
概括

大约35%的组织特异性基因受到昼夜钟的影响,影响衰老和寿命. 了解这种生理节律受影响的组织特异性是解开长寿的基因组机制的关键.

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Circadian Rhythms and Gene Regulation02:19

Circadian Rhythms and Gene Regulation

The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent...
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