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Updated: Jun 23, 2025

Establishment and Characterization of Three Afatinib-resistant Lung Adenocarcinoma PC-9 Cell Lines Developed with Increasing Doses of Afatinib
09:38

Establishment and Characterization of Three Afatinib-resistant Lung Adenocarcinoma PC-9 Cell Lines Developed with Increasing Doses of Afatinib

Published on: June 26, 2019

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在第二代ALK-TKI时代,ALK阳性NSCLC的进展模式,耐药机制和随后的治疗

Lige Wu1, Zihua Zou1,2, Yan Li3

  • 1Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No 17 Panjiayuan Nanli, Chaoyang district, Beijing, 100021, P.R. China.

Journal of translational medicine
|June 20, 2024
PubMed
概括

与crizotinib相比,一线alectinib显著降低了ALK阳性非小细胞肺癌中中枢神经系统的进展. 随后的ALK-TKIs改善了耐药突变患者的结果.

关键词:
阿尔克 (ALK) 是一个在NSCLCLC中,我们可以看到.现实世界的研究研究.电阻 电阻 电阻 电阻 电阻 电阻

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