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Updated: Jun 23, 2025

Detection of Alternative Splicing During Epithelial-Mesenchymal Transition
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替代拼接与无意中介衰变相结合,协调了小鼠神经元发育中的非神经元基因的下调

Anna Zhuravskaya1, Karen Yap1, Fursham Hamid2

  • 1Centre for Developmental Neurobiology, King's College London, London, SE1 1UL, UK.

Genome biology
|June 20, 2024
PubMed
概括

替代拼接 (AS) 与无意中介衰变 (NMD) 相结合,显著影响神经元发育中的基因表达. 我们的发现揭示了数百个AS-NMD事件,特别是涉及磁带外子的事件,这些事件在神经元分化过程中降低非神经元基因的调节.

关键词:
另一个替代拼接方法.定制的转录组注释注释降低非神经元基因的下调.神经元发育的神经元发育无稽之谈中介的衰变是没有意义的.在R包中,R包是R包.

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