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Updated: Jun 23, 2025

Adult and Embryonic Skeletal Muscle Microexplant Culture and Isolation of Skeletal Muscle Stem Cells
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HMGCR 缺乏对骨肌肉发育的影响

Mekala Gunasekaran, Hannah R Littel, Natalya M Wells

    bioRxiv : the preprint server for biology
    |June 21, 2024
    PubMed
    概括

    在HMG CoA减少酶 (HMGCR) 中的致病变体会通过损害骨肌肉发育,增殖和融合,导致四肢腰带肌肉发育不良. 这一发现将HMGCR变异与三个肌肉疾病中的共享机制联系起来.

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