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Updated: Jun 23, 2025

Eukaryotic Polyribosome Profile Analysis
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酵母多A结合蛋白 (Pab1) 在体内控制翻译启动,主要通过阻断mRNA分解和衰变来控制翻译启动

Poonam Poonia1, Vishalini Valabhoju1, Tianwei Li2

  • 1Division of Molecular and Cellular Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD.

bioRxiv : the preprint server for biology
|June 21, 2024
PubMed
概括

多A结合蛋白 (Pab1) 枯竭通过增强mRNA分解和降解来减少mRNA和蛋白质合成. 这一过程依赖于分解酶Dcp2,也影响了组素基因表达.

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