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Updated: Jun 23, 2025

Direct Induction of Hemogenic Endothelium and Blood by Overexpression of Transcription Factors in Human Pluripotent Stem Cells
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Direct Induction of Hemogenic Endothelium and Blood by Overexpression of Transcription Factors in Human Pluripotent Stem Cells

Published on: December 3, 2015

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使用导向分化和转录重编程策略的组合,生成hiPSC衍生的大脑微血管内皮细胞

Aomeng Cui, Ronak Patel, Patrick Bosco

    bioRxiv : the preprint server for biology
    |June 21, 2024
    PubMed
    概括

    研究人员开发了新的重编程的大脑微血管内皮细胞 (rBMECs),以模拟人类血脑屏障 (BBB). 这一进步使得更好地研究神经系统疾病和开发用于大脑的药物.

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    Derivation, Expansion, Cryopreservation and Characterization of Brain Microvascular Endothelial Cells from Human Induced Pluripotent Stem Cells08:04

    Derivation, Expansion, Cryopreservation and Characterization of Brain Microvascular Endothelial Cells from Human Induced Pluripotent Stem Cells

    Published on: November 19, 2020

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    Differentiation of Human Induced Pluripotent Stem Cells to Brain Microvascular Endothelial Cell-Like Cells with a Mature Immune Phenotype09:03

    Differentiation of Human Induced Pluripotent Stem Cells to Brain Microvascular Endothelial Cell-Like Cells with a Mature Immune Phenotype

    Published on: May 19, 2023

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    相关概念视频

    Induced Pluripotent Stem Cells01:13

    Induced Pluripotent Stem Cells

    Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore...
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